Global Dermal Toxicity Testing Market Insights Forecasts to 2033

• The Global Dermal Toxicity Testing Market Size was Valued at USD 2.27 Billion in 2023
• The Market Size is Growing at a CAGR of 8.11% from 2023 to 2033
• The Worldwide Dermal Toxicity Testing Market Size is Expected to Reach USD 4.95 Billion by 2033
• Asia Pacific is Expected to Grow the fastest during the forecast period.

The Global Dermal Toxicity Testing Market Size is Anticipated to Exceed USD 4.95 Billion by 2033, Growing at a CAGR of 8.11% from 2023 to 2033.

Market Overview

Dermal toxicity testing is a type of safety assessment conducted to evaluate the potential harmful effects of a substance when it comes into contact with the skin, intended to characterize the irritation potential, cutaneous and/or systemic toxicity associated with topical administration of compounds, and results used to predict human response. It provides information on health hazards likely to arise from short-term exposure to a test chemical by dermal route, entails evaluation of the safety and efficacy of chemicals, cosmetics, medicines, and personal care products. This testing ensures consumer safety and regulatory compliance by assessing various cutaneous responses such as irritation, sensitization, and corrosion. Reconstructed human epidermis models and cell culture-based assays are the in-vitro dermal testing techniques that have gained popularity as they provide accurate and reliable results and addressing ethical concerns related to animal testing. These methods are being developed to validate the dermal toxicity (irritancy and corrosion) of chemicals and categorize them as irritating or non-irritating to humans. In the field of regulatory toxicology, in vivo studies are still prevailing, and human-derived in vitro models are mostly employed for assessing local skin toxicity. The field of dermal toxicity continues to evolve in order to accurately predict dermal responses in humans to topically applied chemicals.

Report Coverage

This research report categorizes the market for the global dermal toxicity testing market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global dermal toxicity testing market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global dermal toxicity testing market.

Driving Factors

The imposition of strict guidelines and stringent regulations by regulatory bodies such as the USFDA, ECHA, and ICH drive the demand for dermal toxicity testing to ensure the safety of consumers. Technological advancements such as the development of in vitro testing systems, predictive toxicology models, and advanced computational approaches have significantly improved the efficiency and effectiveness of dermal toxicity testing, propelling the market growth. The growing awareness among consumers about product safety including potential risks associated with skincare care products is driving the global dermal toxicity market. The growing emphasis on sustainable practices for reducing animal testing is further promoting the market.

Restraining Factors

The lack of standardized protocols and methodologies for dermal toxicity testing is restraining the global dermal toxicity testing market.  

Market Segmentation

The global dermal toxicity testing market share is classified into type, testing method, test type, and end-use.

• The service segment dominated the market with the largest revenue share in 2023.

Based on the type, the global dermal toxicity testing market is categorized into product and services. Among these, the service segment dominated the market with the largest revenue share in 2023. Service segment is further categorized as inhouse and outsource services. The growing trend of collaboration with CROs to outsource dermal toxicity testing and the application of cutting-edge technology for improving the speed and accuracy of dermal toxicity testing are driving the market.

• The in-vitro testing segment accounted for the largest revenue share of the global dermal toxicity testing market in 2023.

Based on the testing method, the global dermal toxicity testing market is categorized into in-vivo testing, in-vitro testing, and in-silico modeling. Among these, the in-vitro testing segment accounted for the largest revenue share of the global dermal toxicity testing market in 2023. In-vitro testing models mimic the complexity of human skin for more accurate predictions. Human Epidermis (RhE) model and cell culture methods are the in vitro methods being used to categorize chemicals as irritating or non-irritating to humans. The advancements in cell culture technologies are driving the market in the in-vitro testing segment.

• The skin sensitization test segment dominated the market with the largest revenue share in 2023.

Based on the test type, the global dermal toxicity testing market is categorized into skin irritation tests, skin sensitization tests, skin corrosion tests, and phototoxicity tests. Among these, the skin sensitization segment dominated the market with the largest revenue share in 2023. The dermal toxicity test for skin sensitization evaluates a chemical capacity to influence the immune system to the point where the second contact causes a more severe reaction than the initial one. There is a rising prominence of invitro assays for skin sensitization which promote market growth.

• The healthcare industry segment accounted for the largest revenue share of the global dermal toxicity testing market in 2023.

Based on the end-use, the global dermal toxicity testing market is categorized into healthcare industry, cosmetics & personal care products industry, chemical industry, and others. Among these, the healthcare industry segment accounted for the largest revenue share of the global dermal toxicity testing market in 2023. The potential health risks are determined by using the dermal toxicity testing method. Collaboration and outsourcing services are significantly driving the market growth in the healthcare industry segment.

Regional Segment Analysis of the Global Dermal Toxicity Testing Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the global dermal toxicity testing market over the predicted timeframe.

North America is projected to hold the largest share of the global dermal toxicity testing market over the forecast period. The rising demand for in-vitro dermal toxicology testing products drives market in the region. Substantial investments in the advancement of dermal toxicity testing methods are significantly contributing to the market growth. Additionally, consumer awareness and the growing emphasis on product safety contribute to driving the market.

Asia Pacific is expected to grow at the fastest CAGR growth of the global dermal toxicity testing market during the forecast period. The presence of a booming cosmetics and personal care sector, particularly in China, India, and South Korea surges the demand for dermal toxicity testing. The implementation of stricter safety standards for chemicals and cosmetics by regulatory bodies across the region promotes market growth. Further, the increasing focus on research and innovation, and consumer demand for safe products are anticipated to drive the market in the region.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the global dermal toxicity testing market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• SGS S.A.
• Eurofins Scientific Inc
• Qiagen N.V.
• Charles River Laboratories International, Inc.
• Intertek Group
• Merck KgaA
• Covance, Inc
• GE Healthcare
• QIMA LTD
• Thermo Fisher Scientific, Inc.
• Catalent, Inc.
• MatTek Corporation
• InVivo Biosystems
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments

• In January 2023, Eurofins Scientific expanded its presence in the Indian Pharmaceutical market with new state-of-the-art Hyderabad campus, offering comprehensive services to pharmaceutical and biotech companies in the areas of synthetic organic chemistry, analytical R&D, bioanalytical services (for both large and small molecules), in-vivo pharmacology, safety toxicology and formulation R&D. The lab would provide safety toxicology testing along with other testing which would benefit company in expanding its geographical footprint.

• In January 2021, Charles River Laboratories International, Inc. announced that it has entered into a strategic partnership with Cypre, Inc., a biotechnology company that is using 3D hydrogel technology to advance the understanding of the tumor microenvironment and predict therapeutic efficacy.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2033. Spherical Insights has segmented the global dermal toxicity testing market based on the below-mentioned segments: 

Global Dermal Toxicity Testing Market, By Type

• Product
• Services

Global Dermal Toxicity Testing Market, By Testing Method

• In-Vivo Testing
• In-Vitro Testing
• In-Silico Modeling

Global Dermal Toxicity Testing Market, By Test Type

• Skin Irritation Tests
• Skin Sensitization Tests
• Skin Corrosion Tests
• Phototoxicity Tests

Global Dermal Toxicity Testing Market, By End-Use

• Healthcare Industry
• Cosmetics & Personal Care Products Industry
• Chemical Industry
• Others

Global Dermal Toxicity Testing Market, Regional Analysis

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • Uk
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa