Global Medical Nitrous Oxide Market Insights Forecasts to 2033

• The Global Medical Nitrous Oxide Market Size was Estimated at USD 1.75 Billion in 2023
• The Market Size is Expected to Grow at a CAGR of around 6.52% from 2023 to 2033
• The Worldwide Medical Nitrous Oxide Market Size is Expected to Reach USD 3.29 Billion by 2033
• Asia Pacific is predicted to grow at the fastest CAGR throughout the projection period

The Global Medical Nitrous Oxide Market Size is predicted to exceed USD 3.29 Billion by 2033, growing at a CAGR of 6.52% from 2023 to 2033. The market growth is accompanied by the increasing prevalence of chronic diseases, a rising proportion of the geriatric population, statistical growth in surgeries and dental treatments, and extensive usage of nitrous oxide in anesthesia and analgesia methods.

Market Overview

The medical nitrous oxide market involves manufacturing, distributing, and utilizing nitrous oxide for medical applications, primarily used for its anesthetic and analgesic properties. Nitrous oxide (N₂O), a non-flammable gas, is the least potent inhalational anesthetic and is often combined with volatile anesthetics. It is used for general anesthesia, procedural sedation, dental anesthesia, and treating severe pain. Nitrous oxide is referred to as laughing gas and dinitrogen monoxide. Nitrous oxide is produced by heating ammonium nitrate to 245-270°C, forming compounds like ammonia, nitric acid, nitrogen, and nitrogen dioxide, which are purified and separated. Pharmacologically, nitrous oxide is primarily an antagonist of NMDA receptors, with minimal effect on GABAA receptors, and has stimulatory effects on dopamine, α1-adrenergic, α2-adrenergic, and opioid receptors.

The rising occurrence of chronic disease among people escalates the need for nitrous oxide to relieve the pain associated with abnormal conditions, resulting in the nitrous oxide market growth. For instance, the data provided in the Journal PLoS One indicates that chronic diseases significantly affect India's geriatric population, especially in rural and urban areas. Among all chronic diseases, 68% are caused by diabetes and hypertension. According to the US Department of Health and Human Services, 129 million people in the U.S. have at least one major chronic disease, including cardiovascular diseases, diabetes, cancer, hypertension, etc.

The Chronic Disease Unit is the largest unit under the Department of Epidemiology at Columbia University Mailman School of Public Health and aims to extend health span and lifespan while reducing the chronic disease burden and associated disparities both locally and globally. Their research focuses on understanding the causes, distribution, prevention, and treatment of chronic diseases such as cardiovascular disease, cancer, diabetes, hypertension, obesity, Alzheimer's disease, etc. Therefore, reducing the grievance of chronic diseases requires various medications and pain-relieving agents, and several surgical procedures require anesthesia for ingestion in patients for the smooth conduct of surgical operations. Nitrous oxide is widely used by healthcare professionals during operations in the hospital as it has lower solubility in blood and tissues and gives faster anesthetic activity. Considering all the optimistic aspects of nitrous oxide, it concludes that the rising need for nitrous oxide in the medical sector accelerates medical nitrous oxide growth.

Report Coverage

This research report categorizes the global medical nitrous oxide market based on various segments and regions, forecasts revenue growth, and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global medical nitrous oxide market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global medical nitrous oxide market.

Driving Factors

Upsurge in the non-invasive surgical operations:

The increasing acceptance of minimally invasive surgical procedures, including endoscopy and laparoscopy, leading to demand for nitrous oxide as an anesthetic, fuels the market growth. In addition to reducing the healing process and improving cosmetic results, these operations enable the patient to respond and prevent pain. These procedures are more prevalent than their additional conventional counterparts, which increases the need for medical nitrous oxide. The market is anticipated to grow further owing to its positive outcome in the healthcare sector.

Extensive usage of nitrous oxide as a sedative and analgesic agent:

In healthcare organizations and hospitals, nitrous oxide is frequently used as a sedative and pain reliever, especially during minor surgical procedures, delivery, and dental procedures. The market for medical nitrous oxide is growing owing to the rising incidence of chronic pain disorders and the growing need for pain relief treatments. Its evolution is going to be aided by the sedative effects of nitrous oxide used in therapeutic and diagnostic operations.

Restraining Factors

The lack of understanding and awareness among healthcare professionals and patients about the benefits and safety-related issues of nitrous oxide in medical and dental procedures is a significant barrier to its adoption.

Market Segmentation

The global medical nitrous oxide market share is classified into product, application, and end-user.

• The gaseous nitric oxide segment dominated the global medical nitrous oxide market in 2023 and is anticipated to grow at a significant CAGR throughout the forecast period.

Based on the product, the global medical nitrous oxide market is categorized into liquid nitrous oxide and gaseous nitrous oxide. Among these, the gaseous nitric oxide segment dominated the global medical nitrous oxide market in 2023 and is anticipated to grow at a significant CAGR throughout the forecast period. The dominance of this segment is attributed to minimal adverse effects, inhalational characteristics, relief of pain rapidly, effective sedating agent, patient compliance, widespread adaptability, provision of accurate dosing, ease of administration, extensive usage in dental and surgical procedures, and promotes the state of relaxation and cooperation.

• The anesthesia segment accounted for the largest share in 2023 and is expected to grow at a substantial CAGR throughout the projected timeframe.

Based on the application, the global medical nitrous oxide market is categorized into pain relief, cryosurgery, surgical insufflation, and anesthesia. Among these, the anesthesia segment accounted for the largest share in 2023 and is expected to grow at a substantial CAGR throughout the projected timeframe. The segment growth is owing to rapid anesthetic effects that increase the demand for nitrous oxide in emergencies, increasing the number of dental surgeries escalates the need for anesthetics, reduces the incidence of chronic post-surgical pain, widely used to relieve neuropathic pain, and availability of various delivery system for the ingestion of the nitrous oxide to induce anesthesia before surgeries.

• The home healthcare segment held the largest share in 2023 and is predicted to grow at a significant CAGR throughout the projected timeframe.

Based on the end-user, the global medical nitrous oxide market is categorized as home healthcare, research institutions, hospital, and academics. Among these, the home healthcare segment held the largest share in 2023 and is predicted to grow at a significant CAGR throughout the projected timeframe. This is attributed to the evolving healthcare structures and a growing need for home-based healthcare services. Medical nitrous gas emerges as a viable choice for pain management and specific medical procedures beyond conventional healthcare institutions, demand for it in home healthcare settings is expanding, home healthcare simplicity, adaptability, and individualized approach towards home healthcare.

Regional Segment Analysis of the Global Medical Nitrous Oxide Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the global medical nitrous oxide market over the predicted timeframe.

North America is anticipated to hold the largest share of the global medical nitrous oxide market over the predicted timeframe. The advanced healthcare infrastructure, extensive usage, strong market demand, and significant presence of major players in the medical nitrous oxide market in North America, the region's vital significance and ability to shape the dynamics and trends of the medical nitrous oxide market during the given time frame, technological innovations in healthcare, including improvements in patient and anesthetic monitoring systems, are centered on the nation, development of advanced tools and methods for the safe and effective administration of medicinal nitrous oxide contributes to the market dominance in North America.

Asia Pacific is anticipated to grow at the fastest CAGR throughout the projected timeframe. This is attributed to the adaptability of nitrous oxide in medical sectors, raising awareness of the benefits of nitrous oxide in healthcare organizations, innovations in the healthcare infrastructure, availability of sophisticated equipment for the delivery of nitrous oxide during surgical procedures, an increasing proportion of surgical procedures, and robust manufacturing plant and storage capacity in China, rising investments in the hospitals for the development of advanced instruments.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the global medical nitrous oxide market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Air Liquide
• SOL SpA
• Southern Gas Limited
• Carbide and Chemicals
• Steelman Gases Pvt. Ltd.
• Norco Inc.
• CalOx
• Oxygen and Argon Works Ltd.
• Ellenbarrie Industrial Gases
• Gulf Cryo
• Matheson Tri-Gas Inc.
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments

• In February 2024, Veolia launched the first processing lines for nitrous oxide canisters in the UK. Veolia has developed a system to process items safely, aiming to reduce greenhouse gas emissions. The system captures gas from canisters, separates nitrogen and oxygen components, and safely vents the gases before recycling them. The canisters are sourced from commercial waste collections, street cleaning, and illegal store seizures. The system has a warming power nearly 300 times that of carbon dioxide.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2023 to 2033. Spherical Insights has segmented the global medical nitrous oxide market based on the below-mentioned segments:

Global Medical Nitrous Oxide Market, By Product

• Liquid Nitrous Oxide
• Gaseous Nitric Oxide

Global Medical Nitrous Oxide Market, By Application

• Pain Relief
• Cryosurgery
• Surgical Insufflation
• Anesthesia

Global Medical Nitrous Oxide Market, By End-User

• Home Healthcare
• Research Institutions
• Hospital
• Academics

Global Medical Nitrous Oxide Market, By Regional

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa