Global Nucleic Acid Isolation & Purification Market Insights Forecasts to 2033

• The Global Nucleic Acid Isolation & Purification Market Size was Valued at USD 5.5 Billion in 2023
• The Market Size is Growing at a CAGR of 8.38% from 2023 to 2033
• The Worldwide Nucleic Acid Isolation & Purification Market Size is Expected to Reach USD 12.3 Billion by 2033
• Asia-Pacific is Expected to Grow the fastest during the forecast period.

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The Global Nucleic Acid Isolation & Purification Market Size is Anticipated to Exceed USD 12.3 Billion by 2033, Growing at a CAGR of 8.38% from 2023 to 2033.

 

Market Overview

Nucleic acid isolation & purification is a set of molecular biology techniques for extracting and purifying DNA and RNA  in downstream applications such as PCR, sequencing, cloning, and gene expression analysis. It is a crucial step in molecular biology and recombinant DNA procedures, having widespread application in numerous life science research, genetic engineering, forensics, and molecular diagnostics applications. The continuous advancements in the fields of genomics, proteomics, and personalized medicine surge the growing need for reliable and efficient methods of nucleic acid extraction in molecular biology laboratories for isolating and purifying DNA or RNA from various biological samples. Multiple methods of nucleic acid isolation and purification are being employed in enzyme-linked immunosorbent assays (ELISA), polymerase chain reaction (PCR), or lateral flow assays, offering unparalleled flexibility, allowing for the customization of assays to meet specific diagnostic needs, assisting in the development of a wide range of diagnostic tests associated diseases, pathogens, and analytes. Identification of molecular markers that can help identify disease stage, treatment response, and other patient outcomes, thereby facilitating the development of personalized medicine. Technological innovations like magnetic bead technology and highly efficient microfluidics and lab-on-a-chip technologies, integration with molecular diagnostics, personalized medicine and genomics, sustainability, and green chemistry are leveraging future market opportunities for nucleic acid isolation and purification.

 

Report Coverage             

This research report categorizes the market for the global nucleic acid isolation & purification market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global nucleic acid isolation & purification market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global nucleic acid isolation & purification market.  

 

Driving Factors

The growth in genomics & enzymology-based research including studying nucleic acids that help gain insights into diseases is driving the demand for nucleic acid isolation and purification. Thus, the growing demand for molecular diagnostics and the increasing prevalence of infectious diseases and genetic disorders worldwide is driving the market. Further, the adoption of sequencing for the clinical diagnosis of cancer is contributing to market growth. The advancement in biotechnology and genomic research along with the enhanced potential of molecular biology and advancement in precision medicine and adoption of personalized medicine are further augmenting market growth. The participation of leading market players in a moderate level of merger and acquisition (M&A) activity for gaining access to new nucleic acid isolation & purification facilities, expanding product portfolios, and improving competencies are significantly propelling the global nucleic acid isolation and purification market. Further, the growing need for the development of nucleic acid-based goods such as DNA vaccines and double-stranded RNA  non-coding molecules has driven the market demand for nucleic acid isolation and purification.

 

Restraining Factors

The stringent regulations related to genomics, forensics, molecular diagnostics, and genetic engineering as well as the high cost of reagents and consumables used for nucleic acid isolation and purification are restraining the market. Further, the lack of standardization across laboratories is also hampering the global nucleic acid isolation & purification market.

 

Market Segmentation

 

The global nucleic acid isolation & purification market share is classified into product, type, method, application, and end-use.

• The kit product type segment dominated the market with the largest revenue share in 2023.

Based on the product, the global nucleic acid isolation & purification market is categorized into kits, reagents, and instruments. Among these, the kit product type segment dominated the market with the largest revenue share in 2023. A wide range of DNA and RNA isolation and purification kits are used for preparing high-quality samples and libraries for downstream analysis. The emphasis on developing advanced kits by the key market players is augmenting the market growth.

 

• The plasmid DNA isolation and purification type segment is expected to grow at the fastest pace in the global nucleic acid isolation & purification market during the forecast period.

Based on the type, the global nucleic acid isolation & purification market is categorized into plasmid DNA isolation & purification, total RNA isolation & purification, circulating nucleic acid isolation & purification, genomic DNA isolation & purification, messenger RNA  isolation & purification, microRNA isolation & purification, and others. Among these, the plasmid DNA isolation and purification type segment is expected to grow at the fastest pace in the global nucleic acid isolation & purification market during the forecast period. Plasmid DNA isolation and purification involves automated isolation of high molecular weight DNA for genome assembly and long-read sequencing. There is widespread utilization of purified plasmid DNA in various molecular biology applications. Further, the investment in DNA isolation & purification solutions and the rising research on gene therapies and genetic vaccination plasmid DNA are contributing to the market growth.

 

• The magnetic beads segment accounted for the largest revenue share of the global nucleic acid isolation & purification market in 2023.

Based on the method, the global nucleic acid isolation & purification market is categorized into column-based, magnetic beads, reagent-based, and others. Among these, the magnetic beads segment accounted for the largest revenue share of the global nucleic acid isolation & purification market in 2023. Magnetic beads serve as versatile platforms for the immobilization of biomolecules such as antibodies, nucleic acids, and enzymes for the separation of nucleic acid from crude samples, enabling the development of highly sensitive and specific diagnostic assays. The increasing adoption of magnetic beads owing to their improved assay performance and better isolation and purification of DNA and RNA are leveraging the market growth.

 

• The personalized medicine segment is expected to grow at the fastest CAGR during the forecast period.

Based on the application, the global nucleic acid isolation & purification market is categorized into diagnostics, drug discovery & development, personalized medicine, agriculture & animal research, and others. Among these, the personalized medicine segment is expected to grow at the fastest CAGR during the forecast period. Personalized medicine integrates the genetic profiles of patients to guide diagnostic, preventive and treatment decisions. There is rising demand for genomic data in diagnostic and treatment decision-making along with ongoing advancements in genomic research upsurges the market demand in the personalized medicine segment.

 

• The hospitals and diagnostics centers segment dominated the market with the largest share of the global nucleic acid isolation & purification market in 2023.   

Based on the end-use, the global nucleic acid isolation & purification market is categorized into academic research institutes, pharmaceutical & biotechnology companies, contract research organizations, hospitals & diagnostic centers, and others. Among these, the hospitals and diagnostics centers segment dominated the market with the largest share of the global nucleic acid isolation & purification market in 2023. Hospitals and diagnostic centers are the primary healthcare providers, investing heavily in state-of-the-art machinery and technology for nucleic acid isolation and purification. These settings act as the main facilities for patients having significant diagnostic tests, thereby driving the market.

 

Regional Segment Analysis of the Global Nucleic Acid Isolation & Purification Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

 

North America is anticipated to hold the largest share of the global nucleic acid isolation & purification market over the predicted timeframe.

 

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North America is projected to hold the largest share of the global nucleic acid isolation & purification market over the forecast period. The presence of leading biotechnology and pharmaceutical companies in the region is contributing to market growth. The significant government investments in genomics and molecular biology research are significantly driving the market in the region. The increasing awareness among healthcare professionals and researchers and the growing demand for personalized medicine and diagnostics are anticipated to propel the market. Further, the automation of products has increased the use of nucleic acid molecular diagnostics which ultimately leads to driving the market.

 

Asia-Pacific is expected to grow at the fastest CAGR growth of the global nucleic acid isolation & purification market during the forecast period. The growing need for the development of nucleic acid-based goods such as DNA vaccines and double-stranded RNA  non-coding molecules has driven the market growth in the region. Furthermore, discovering new pharmaceuticals, mergers, acquisitions, and partnerships contribute to market growth. In addition, the growing patient population, private-public collaborations, and supportive government initiatives are responsible for driving the regional market.

 

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the nucleic acid isolation & purification market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

 

List of Key Companies

• Thermo Fisher Scientific, Inc.
• QIAGEN
• Illumina, Inc.
• Danaher
• F. Hoffmann-La Roche Ltd
• Bio-Rad Laboratories, Inc.
• Takara Bio Inc.
• Promega Corporation
• Merck KGaA
• Agilent Technologies
• New England Biolabs
• Abcam plc.
• PCR Biosystems
• Zymo Research Corporation
• Biogeniux
• Others

 

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

 

Recent Developments

• In July 2023, Australia-based startup Inoviq, and US-based Promega Corporation, announced a joint marketing agreement to co-market Inoviq’s EXO-NET exosome capture technology and Promega Nucleic Acid purification systems worldwide.
• In May 2022, Thermo Fisher Scientific and Qatar Genome Program (QGP), a member of Qatar Foundation (QF), have partnered intending to accelerate genomic research and clinical applications of predictive genomics in Qatar as a step toward expanding the benefits of precision medicine across Arab populations globally.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2033. Spherical Insights has segmented the global nucleic acid isolation & purification market based on the below-mentioned segments: 

 

Global Nucleic Acid Isolation & Purification Market, By Product

• Kits
• Reagents
• Instruments

 

Global Nucleic Acid Isolation & Purification Market, By Type

• Plasmid DNA Isolation & Purification
• Total RNA Isolation & Purification
• Circulating Nucleic Acid Isolation & Purification
• Genomic DNA Isolation & Purification
• Messenger RNA  Isolation & Purification
• MicroRNA Isolation & Purification
• Others

 

Global Nucleic Acid Isolation & Purification Market, By Method

• Column-Based
• Magnetic Beads
• Reagent-Based
• Others

 

Global Nucleic Acid Isolation & Purification Market, By Application

• Diagnostics
• Drug Discovery & Development
• Personalized Medicine
• Agriculture & Animal Research
• Others

 

Global Nucleic Acid Isolation & Purification Market, By End-Use

• Academic Research Institutes
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations
• Hospitals & Diagnostic Centers
• Others

 

Global Nucleic Acid Isolation & Purification Market, Regional Analysis

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • Uk
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa