Global Organ-on-Chip Market Insights Forecasts to 2033

• The Global Organ-on-Chip Market Size was Valued at USD 58.08 Million in 2023
• The Market Size is Growing at a CAGR of 13.12% from 2023 to 2033
• The Worldwide Organ-on-Chip Market Size is Expected to Reach USD 199.31 Million by 2033
• Asia Pacific is expected to Grow the fastest during the forecast period.

The Global Organ-on-Chip Market Size is Anticipated to Exceed USD 199.31 Million by 2033, Growing at a CAGR of 13.12% from 2023 to 2033.

Market Overview

Organ-on-a-chips are a micro-engineered biomimetic system that replicates the structure and functional properties of human tissue. Small devices containing human cells are utilized to simulate the environment of human organs, such as blood flow and respiratory movements, and serve as synthetic habitats for testing new medications. Organ-on-a-chip technologies can overcome the limits of traditional two-dimensional cell culture approaches, allowing for the creation of models that imitate the three-dimensional arrangement of various cell types in a more physiologically accurate manner. Organ-on-a-chip technology could give an alternative platform for drug testing. From an economic aspect, the faster turnaround of analysis enabled by organ-on-a-chip technology has the potential to minimize drug testing costs. Furthermore, using human cells can result in higher precision. The market is primarily driven by factors such as the need for alternatives to animal testing and early detection of medication responses and toxicity. Furthermore, organ-on-chip technology does not just apply to the liver, lungs, kidneys, and heart. Stakeholders in this market are doing their best and focused on increasing the organ's applications and sites using this technology. Microfluidic devices have been developed to replicate the function of organs such as the lungs and heart. The lung-on-a-chip was designed to imitate the structural, functional, and mechanical features of the human alveolar-capillary user interface.

Report Coverage

This research report categorizes the market for the global organ-on-chip market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global organ-on-chip market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global organ-on-chip market.

Driving Factors

The organ-on-chip sector is being supported by factors such as alternatives for animal testing, the need for the initial identification of remedy toxicity, and unique product introduction. Elevations in technology are also accountable for boosting the growth of the market. Developments in healthcare technologies, as well as an increase in the rate of organ transplantation, are likely to drive up demand for organs on chips. Pharmaceutical businesses' increasing attempts to finance and investigate drug reuse utilizing organ-on-chip patterns are also expected to accelerate the expansion of the organ-on-chip market. The use of organ-on-chip technology is driving market expansion such as advancement in cell biology, microfabrication, and microfluidics, which are offering attractive prospects for industry growth.

Restraining Factors

The high cost of organ chip devices, as well as the development of organ-on-chip (OOC) technology, are projected to impede market expansion. In addition, rigorous regulations are expected to pose a challenge to the organ-on-chip market throughout the forecast period.

Market Segmentation

The global organ-on-chip market share is classified into application, organ type, and end users.

• The drug discovery segment is expected to boost the growth of the market during the forecast period.

Based on the application, the global organ-on-chip market is categorized into disease modeling, drug discovery, and toxicity testing. Among these, the drug discovery segment is expected to boost the growth of the market during the forecast period. The drug discovery section is the largest, owing to its significance in pharmaceutical advancement and research. Organ-on-chip technology has aided drug development by providing more physiologically realistic models that better represent human organ functioning and interaction than standard in vitro and animal models. These microscale platforms allow researchers to examine therapeutic efficacy, toxicity, and safety in a more accurate and cost-effective manner, decreasing the drug development timetable and lowering the risk of late-stage failures in clinical trials.

• The liver organ type dominates the market over the forecast period.

Based on the organ type, the global organ-on-chip market is categorized into lungs, heart, liver, and kidney. Among these, the liver organ type dominates the market over the forecast period. Liver-on-chip platforms have various advantages over traditional approaches, including greater predictability, reduced reliance on animal testing, and the capacity to screen drug candidates at huge volumes. Liver-on-chip models are used to simulate physiological conditions, such as toxicity testing and disease modeling. It is one of the largest research and development platforms, with a wide range of commercial products available on the market. Liver-on-chip platforms are used for a variety of applications, including drug discovery, toxicity testing, disease modeling, and personalized medicine, which serve a major portion of the medical business.

• The pharmaceuticals and biotech companies are holding the largest market share during the projected timeframe.

Based on end-users, the global organ-on-chip market is categorized into pharmaceuticals and biotech companies, contract research organizations, and academic & research institutes. Among these, the pharmaceuticals and biotech companies are holding the largest market share during the projected timeframe. Pharmaceutical and biotechnology businesses are the largest end-user group in the organ-on-chip market, owing to their significant expenditure in R&D operations aimed at discovering and developing new medications and cures. These businesses offer resources, skills, and facilities dedicated to furthering research and development into novel solutions for health care. Moreover, these businesses work with universities, educational research organizations, and contract research organizations (CROs) to appraise and optimize organ-on-chip technology, hence accelerating its wider adoption and implementation in the pharmaceutical industry.

Regional Segment Analysis of the Global Organ-on-Chip Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is projected to hold the largest share of the global organ-on-chip market over the forecast period.

North America is projected to hold the largest share of the global organ-on-chip market over the forecast period. North America has historically been the greatest market for organ-on-chip technology. It is the main location for the implementation of this technology due to the presence of numerous pharmaceutical businesses, research institutions, and technology developers. This location has a strong environment for biotech and life science that encourages breakthroughs. Regulatory authorities such as the FDA consult with stakeholders to investigate potential applications in medication discovery and safety evaluations.

Asia Pacific is expected to grow at the fastest CAGR growth of the global organ-on-chip market during the forecast period. Increased demand for customized medicines, growth in medical facilities, and the existence of a major pharmaceutical market all contribute to its status as the fastest-expanding market.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the global organ-on-chip market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• SynVivo
• Cherry Biotech
• InSphero AG
• Elveflow
• Ascendance Biotechnology, Inc.
• Draper
• Mimica
• Zyoxel Ltd.
• AxoNet Medical Systems, Inc.
• AxoSim Technologies
• Nortis, Inc.
• Mimetas
• MIMETAS B.V.
• Tara Biosystems
• Kirkstall Ltd.
• Others

Key Market Developments

• In June 2023, MatTek Life Sciences established a strategic relationship with AIM Biotech, making the AIM Biotech portfolio available for sale through MatTek.

• In June 2023, Emulate introduced Emulate Chip-A1 to expand its applications in the oncology and cosmetics areas.  

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2033. Spherical Insights has segmented the global organ-on-chip market based on the below-mentioned segments: 

Global Organ-on-Chip Market, By Application

• Disease Modeling
• Drug Discovery
• Toxicity Testing

Global Organ-on-Chip Market, By Organ Type

• Lungs
• Heart
• Liver
• Kidney

Global Organ-on-Chip Market, By End-Users

• Pharmaceuticals and Biotech Companies
• Contract Research Organizations
• Academic & Research Institutes

Global Organ-on-Chip Market, By Regional

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • Uk
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa