Global Polymerase Chain Reaction Market Insights Forecasts to 2033

• The Global Polymerase Chain Reaction Market Size was Valued at USD 12.21 Billion in 2023
• The Market Size is Growing at a CAGR of 7.8% from 2023 to 2033
• The Worldwide Polymerase Chain Reaction Market Size is expected to Reach USD 26.04 Billion by 2033
• Asia-Pacific Market is expected to grow the fastest during the forecast period

The Global Polymerase Chain Reaction Market Size is Anticipated to Exceed USD 26.04 Billion by 2033, Growing at a CAGR of 7.8% from 2023 to 2033.

Market Overview

Polymerase chain reaction (PCR) is a molecular biology technique used to amplify and analyze DNA. It enables the exponential replication of a specific DNA segment, allowing researchers to generate a large number of copies of a target DNA sequence. Polymerase chain reaction (PCR) is used for amplifying a particular DNA segment using a thermal cycling procedure. Ongoing technological progress in PCR aims to enhance specificity, scalability, and reliability in DNA amplification, resulting in the rapid generation of millions of target sequence amplicons. This method happens to be an in vitro amplification technique. The rising incidence of diverse infectious diseases and various genetic disorders has led to an increased need for these methodologies. The growth of the polymerase chain reaction (PCR) market was notably increased by the COVID-19 pandemic. The clinical diagnostic segment experienced a favorable influence on the PCR market, driven by the rising demand. In addition to these, the viral culture tests were not recommended by authorities, healthcare professionals suggested diagnostic tests for individuals displaying COVID-19 symptoms, with RT-PCR being widely utilized in the testing of such populations. The anticipated growth of the global polymerase chain reaction market during the forecast period is attributed to swift technological progress in PCR, leading to the development of highly sensitive and optimized detection instruments.

Report Coverage

This research report categorizes the market for the global polymerase chain reaction market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global polymerase chain reaction market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global polymerase chain reaction market.

Driving Factors

Ongoing technological advancements in PCR methods, such as real-time PCR and digital PCR, have enhanced the efficiency, sensitivity, and specificity of the technique. These innovations contribute to the overall growth of the PCR market. The amplification of a shorter DNA region in vitro is facilitated by the polymerase chain reaction, a process primarily driven by enzymes. The anticipated growth in the market for this technology is attributed to the increased demand for innovative devices and advancements. Miniature devices are now available on the market due to recent innovations, and these devices provide a lot of clinical perks for both patients and healthcare professionals. Investments in healthcare infrastructure, especially in emerging markets, have led to the adoption of advanced diagnostic technologies, including PCR. Government initiatives and private investments in healthcare contribute to market growth. The trend towards personalized medicine and pharmacogenomics, where treatments are tailored to an individual's genetic structure, has increased the demand for molecular diagnostic tools like PCR for genetic testing. Collaborations and partnerships between pharmaceutical companies, diagnostic laboratories, and research institutions drive innovation and the development of new PCR-based technologies. Such collaborations often lead to the commercialization of novel products.

Restraining Factors

Research advancements that result in the development of alternative nucleic acid amplification techniques are the main factors limiting the growth of the global polymerase chain reaction market. Unlike PCR, which requires temperature cycling to denature, anneal, and extend DNA, isothermal amplification techniques operate at a constant temperature. For instance, include Loop-Mediated Isothermal Amplification (LAMP), Recombinase Polymerase Amplification (RPA), and Helicase-Dependent Amplification (HDA). Isothermal methods are often faster and simpler than PCR, requiring fewer steps and less sophisticated equipment.

Market Segmentation

The global polymerase chain reaction market share is classified into type, product, application, and end-user

• The digital PCR segment is expected to hold the largest share of the global polymerase chain reaction market during the forecast period.   

Based on type, the global polymerase chain reaction market is divided into conventional PCR, standard PCR, real time PCR, digital PCR and others. Among these, the digital PCR segment is expected to hold the largest share of the polymerase chain reaction market during the forecast period. One of the primary advantages of digital PCR is its ability to provide absolute quantification of nucleic acids. Unlike conventional PCR, which provides relative quantification, digital PCR can accurately determine the exact number of target molecules present in a sample. Digital PCR is well-suited for detecting and quantifying rare mutations in a background of wild-type sequences. This is particularly important in cancer research and diagnostics, where the identification of low-frequency mutations can have significant clinical implications.

• The consumables & reagents segment is expected to grow at fastest pace in the global polymerase chain reaction market during the forecast period.    

Based on the product, the global polymerase chain reaction market is divided into software & services, consumables & reagents, instruments. The consumables & reagents segment is expected to grow at fastest pace in the polymerase chain reaction market during the forecast period. The expansion of this sector is linked to the escalating prevalence of infectious and chronic illnesses, a growing need for consumables and reagents in diverse diagnostic assays, and an upsurge in the introduction of new products. The rising incidence of infectious diseases like COVID-19 is fueling an increasing need for reagents and consumables globally. Ongoing advancements in DNA or RNA amplification techniques have resulted in a heightened market demand for these technologies.

• The medical segment is expected to grow at greatest pace in the global polymerase chain reaction market during the forecast period.

Based on the application, the global polymerase chain reaction market is divided into medical (clinical, pathology testing, oncology testing, blood screening, research, forensics, others), non-medical (food, others). The medical segment is expected to grow at greatest pace in the polymerase chain reaction market during the forecast period. The widespread use of PCR tests in clinical diagnostics and research, particularly in the examination of diseases and drug development, has contributed to their high adoption rate. Additionally, the rising utilization of PCR in identifying SARS-CoV-2 infections, as well as in drug development and research efforts, is driving an increased demand for these tests.

• The pharmaceutical & biotechnology industries segment are expected to grow at fastest pace in the global polymerase chain reaction market during the forecast period.    

Based on the end-user, the global polymerase chain reaction market is divided into clinical diagnostics labs & hospitals, pharmaceutical & biotechnology industries, academic & research organizations, other end-users. The pharmaceutical & biotechnology industries segment are expected to grow at fastest pace in the polymerase chain reaction market during the forecast period. The polymerase chain reaction (PCR) market is expected to be driven by the biotechnology and pharmaceutical industries. The pharmaceutical and biotechnology industries are expected to see a surge in demand for PCR services due to the rising test volumes and automation in laboratories. Significant advancements in the field of pharmacogenomics, along with the growing popularity of self-diagnosing illnesses, will propel the expansion of the PCR market.

Regional Segment Analysis of the Global Polymerase Chain Reaction Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the global polymerase chain reaction market over the predicted timeframe.

North America is anticipated to hold the largest share of the global polymerase chain reaction market over the predicted timeframe. The expansion is linked to the modernization of healthcare infrastructure and the growing utilization of advanced diagnostic technologies, including PCR technologies, in both research and clinical applications. The surge in growth is credited to the uptake of innovative biotechnologies, increased awareness of PCR products, substantial financial investment in research within national budgets, early access to advanced technologies, and a notable increase in research and development activities in the region. The growth of the regional market is facilitated by the existence of supportive regulations and governmental initiatives aimed at enhancing healthcare infrastructure. Additionally, the high prevalence of diseases and the presence of major industry players in the area contribute to this growth. Moreover, an increase in patient awareness regarding the accessibility of contemporary products for effective diagnosis is a further factor contributing to the expansion. Additionally, as reported in June 2022 by Statistics Canada in partnership with the Canadian Cancer Society and the Public Health Agency of Canada, approximately 233,900 individuals in Canada are projected to receive a cancer diagnosis in 2022. Consequently, the growing incidence of these conditions is expected to drive the implementation of PCR, thereby contributing to market expansion throughout the study's forecast period.

Asia Pacific is expected to grow at the fastest pace in the global polymerase chain reaction market during the forecast period.  Furthermore, an increased pace of product launch in the region due to the rising need for competent assays is probably going to help the region experience faster revenue development. For instance, Singapore-based Lucence Diagnostics announced in June 2020 the introduction of the SARS-CoV-2 RNA RT-PCR test, which is intended to diagnose COVID-19 infections.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the global polymerase chain reaction along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Abbott
• Agilent Technologies, Inc.
• Fluidigm Corporation
• Cytiva
• Cepheid
• Stilla Technologies
• Microsynth AG
• QIAGEN
• F. Hoffmann-La Roche Ltd.
• Stilla
• Atila Biosystems
• Standard BioTools
• Microsynth AG
• Bio-Rad Laboratories, Inc.
• Thermo Fisher Scientific Inc.
• bioMérieux, S.A.
• Enzo Life Science
• Dickinson and Company
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments

• In November 2022, Cepheid introduced the Xpert Xpress MVP, a multiplexed PCR test designed to identify DNA from organisms linked to three specific conditions: bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis. This test enables the detection of these conditions from a single sample, contributing to improved precision in diagnosis and facilitating appropriate antibiotic treatment plans.

• In January 2022, Qiagen partnered with Atila Biosystems and Actome GmbH to utilize QIAcuity digital PCR instruments. Atila Biosystems will offer non-invasive prenatal testing, while Actome broadens the application of QIAcuity from genomics to proteomics.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2033. Spherical Insights has segmented the global polymerase chain reaction market based on the below-mentioned segments:

Global Polymerase Chain Reaction Market, By Type

• Conventional PCR
• Standard PCR
• Real Time PCR
• Digital PCR
• Others

Global Polymerase Chain Reaction Market, By Product

• Software & Services
• Consumables & Reagents
• Instruments

Global Polymerase Chain Reaction Market, By Application

• Medical

• Clinical
• Pathology Testing
• Oncology Testing
• Blood Screening
• Research
• Forensics
• Others

• Non-Medical

• Food
• Others

Global Polymerase Chain Reaction Market, By End-User

• Clinical Diagnostics Labs & Hospitals
• Pharmaceutical & Biotechnology Industries
• Academic & Research Organizations
• Others

Global Polymerase Chain Reaction Market, By Region

• North America
  • US
  • Canada
  • Mexico

• Europe
  • Germany
  • Uk
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East and Africa