Global Protein Therapeutics Market Insights Forecasts to 2033

• The Global Protein Therapeutics Market Size was Valued at USD 341.4 Billion in 2023
• The Market Size is Growing at a CAGR of 5.9% from 2023 to 2033
• The Worldwide Protein Therapeutics Market Size is Expected to Reach USD 605.38 Billion by 2033
• Asia Pacific Market is expected to grow the fastest during the forecast period

The Global Protein Therapeutics Market Size is Anticipated to Exceed USD 605.38 Billion by 2033, Growing at a CAGR of 5.9% from 2023 to 2033.

Market Overview

Therapeutic protein drugs are a type of medicine that is used to treat a variety of diseases such as cancer, metabolic, immunological, hematological, hormonal, genetic, infectious diseases, and others. These drugs have the potential to significantly improve the health of humans. Protein therapy refers to drugs made from proteins that are artificially synthesized. These potent, fast-acting medications deliver tiny protein molecules to the body in precise amounts. Medicine that are genetically engineered versions of naturally occurring human proteins such as human growth hormones (HGH), follicle-stimulating hormones, insulin, fusion proteins, erythropoietin, monoclonal antibodies, and insulin. They can be used to replace a protein that is deficient or lacking in a given condition. They may additionally enhance the supply of a healthy protein, which may reduce the adverse effects of disease or chemotherapy. Global protein therapeutics market is steadily expanding due to rising demand for targeted and personalized therapies. Advances in biotechnology and the rise of chronic diseases are driving market growth, with a particular focus on monoclonal antibodies and recombinant proteins. The global market is primarily driven by the growing focus on personalized treatment. By this, rising R&D activities and expanding healthcare infrastructure are making major contributions to the market.

Report Coverage

This research report categorizes the market for the global protein therapeutics market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the global protein therapeutics market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the global protein therapeutics market.

Driving Factors

The growth of the global protein therapeutics market is driven by increasing the prevalence of various diseases such as cancer, metabolic disorders, genetic disorders, and immunological diseases are expected to propel demand for protein therapeutics. Increasing the investment in the R&D biopharmaceutical sector is driving the advancement of protein therapeutics. These investments help to development in protein engineering, drug discovery, and development of novel and improved protein therapeutics. As the global population ages, the prevalence of age-related illnesses and disorders like Alzheimer's, Parkinson's, macular degeneration, and osteoporosis. Growth of the biosimilars market propelling demand for protein therapeutics. The expiration of the patent for key products is driven by the biosimilar markets. Thus, the manufacturer has an opportunity to develop more affordable alternatives than competitive and easily accessible critical therapies. Technology advancement in protein engineering involving recombinant DNA technology, monoclonal antibody production, and protein expression systems, have revolutionized the development of protein therapeutics. Increasing the demand for personalized medicine treatment is based on the person’s genetics profile, disease characteristics, and response to treatment. Hence, these factors are significantly driving the growth of the global protein therapeutics market during the forecast period.

Restraining Factors

The required high production cost for developing as well as manufacturing products is expected to restrain the growth of the global protein therapeutics markets. The growing elderly population, the rise in the number of chronic diseases, and the increased demand for protein therapies may lead to limited availability and affordability in the upcoming days. Protein physiochemical instability and immunogenicity are majorly restricting growth in the global protein therapies market during the forecast period.

Market Segmentation

The global protein therapeutics market share is classified into product, application, function, and end-user.

• The monoclonal antibodies segment is expected to hold the largest share of the global protein therapeutics market during the forecast period.

Based on the product, the global protein therapeutics market is divided into monoclonal antibodies, insulin, fusion protein, erythropoietin, interferon, human growth hormone, and follicle stimulating hormone. Among these, the monoclonal antibodies segment is expected to hold the largest share of the global protein therapeutics market during the forecast period. The segmental growth can be attributed to these products being widely available, important, and applicable in the treatment of a variety of chronic diseases. Monoclonal antibodies are widely used for the treatment of cancer, and autoimmune disorders. The rising prevalence of these illnesses, combined with advances in antibody engineering and production technologies drive the demand for monoclonal antibodies and contribute the market growth.

• The metabolic disorders segment is expected to hold the largest share of the global protein therapeutics market during the forecast period.   

Based on the application, the global protein therapeutics market is divided into metabolic disorders, immunologic disorders, hematological disorders, cancer, hormonal disorders, genetic disorders, and others. Among these, the metabolic disorders segment is expected to hold the largest share of the global protein therapeutics market during the forecast period. With the increasing prevalence of metabolic disorders, protein therapeutics, including insulin and other related products, are crucial in the management of diabetes, which is contributing to the growth of the metabolic disorders segment.

• The enzymatic and regulatory activity segment is expected to hold the largest share of the global protein therapeutics market during the forecast period.

Based on the function, the global protein therapeutics market is divided into enzymatic and regulatory activity, special targeting activity, vaccines, and protein diagnostics. Among these, the enzymatic and regulatory activity segment is expected to hold the largest share of the global protein therapeutics market during the forecast period. Enzymatic and regulatory activities are important in modulating biological processes and metabolic pathways. They regulate cellular activities, signaling pathways, and enzymatic reactions, making them useful for a variety of therapeutic purposes.

• The healthcare service providers segment is expected to hold the largest share of the global protein therapeutics market during the forecast period.

Based on the end user, the global protein therapeutics market is divided into pharmaceutical companies, healthcare service providers, research organizations, and academic research institutes. Among these, the healthcare service providers segment is expected to hold the largest share of the global protein therapeutics market during the forecast period. The segmental growth can be attributed to the growing emphasis on personalized medicine and patient-centered services, healthcare practitioners are introducing protein therapies into their treatment protocols for a variety of disorders. Healthcare providers have direct contact with a huge number of patients. This ability allows them to provide protein therapies to patients while monitoring their responses.

Regional Segment Analysis of the Global Protein Therapeutics Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• Latin America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the global protein therapeutics market over the predicted timeframe.

North America is anticipated to hold the largest share of the global protein therapeutics market over the predicted timeframe. Increase in the prevalence of chronic diseases, adoption of technologically advanced treatments, strong presence of biopharmaceutical companies, and rise in healthcare expenditure with advanced healthcare infrastructure in the region. Increasing investment in protein therapeutic research the large aging population, and favorable reimbursement policies are contributing to the growth of the regional market. The prevalence of favorable reimbursement medical facilities and improved standard of living of the people. 

Asia Pacific is expected to grow at the fastest pace in the global protein therapeutics market during the forecast period. The growth can be attributed to the rising prevalence of chronic diseases, large population base, and increasing healthcare expenditure. In the Asia Pacific region, the large number of biopharmaceutical companies as well as investment in research and development.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the global protein therapeutics market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of overall competition within the market.

List of Key Companies

• Sanofi
• Baxter International Inc.
• Johnson and Johnson
• Abbott Laboratories
• Amgen Inc.
• Eli Lilly and Company
• Biogen Inc.
• Thermo Fisher Scientific, Inc.
• Teva Pharmaceutical Industries Ltd
• Abbvie Inc.
• Merck and Co., Inc.
• Csl Behring L.L.C.
• Novo Nordisk AS
• F. Hoffmann La Roche Ltd
• Pfizer Inc.
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments

• In February 2024, BioNtech, a next-generation immunotherapy company, and autolus, a clinical-stage biopharmaceutical company, announced the strategic collaboration for CAR-T cell therapy.

• In February 2024, Lumosa Therapeutics, a taiwan-based firm, introduced two phase II clinical trials, LT3001, a candidate for treating acute ischemic stroke (AIS). The phase IIb bright (NCT05403866) trial and phase II Lumosa 203 trial (NCT05198323) are double-blinded, placebo-controlled.

• In January 2022, Thermo Fisher Scientific, Inc. paid US$ 1.85 billion in cash to acquire PeproTech. PeproTech, a privately held company, supplies bioscience reagents such as growth factors and cytokines to the cell and gene therapy industries, as well as other cell culture-based applications. PeproTech is headquartered in Cranbury, New Jersey.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2033. Spherical Insights has segmented the global protein therapeutics market based on the below-mentioned segments: 

Global Protein Therapeutics Market, By Product

• Monoclonal Antibodies
• Insulin
• Fusion Protein
• Erythropoietin, Interferon
• Human Growth Hormone
• Follicle Stimulating Hormone

Global Protein Therapeutics Market, By Application

• Metabolic Disorders
• Immunologic Disorders
• Hematological Disorders
• Cancer
• Hormonal Disorders
• Genetic Disorders
• Others

Global Protein Therapeutics Market, By Function

• Enzymatic
• Regulatory Activity
• Special Targeting Activity
• Vaccines
• Protein Diagnostics

Global Protein Therapeutics Market, By End User

• Pharmaceutical companies
• Healthcare Service Providers
• Research Organizations
• Academic Research Institutes

Global Protein Therapeutics Market, By Region

• North America
• US
• Canada
• Mexico
• Europe
• Germany
• Uk
• France
• Italy
• Spain
• Russia
• Rest of Europe
• Asia Pacific
• China
• Japan
• India
• South Korea
• Australia
• Rest of Asia Pacific
• South America
• Brazil
• Argentina
• Rest of South America
• Middle East & Africa
• UAE
• Saudi Arabia
• Qatar
• South Africa
• Rest of the Middle East & Africa