United States Bone Graft Substitutes Market Insights Forecasts to 2033

• The U.S. Bone Graft Substitutes Market Size was valued at USD 945.1 Million in 2023.
• The Market Size is Growing at a CAGR of 5.39% from 2023 to 2033
• The U.S. Bone Graft Substitutes Market Size is Expected to Reach USD 1598.1 Million by 2033

The U.S. Bone Graft Substitutes Market Size is Anticipated to Exceed USD 1598.1 Million by 2033, Growing at a CAGR of 5.39% from 2023 to 2033.

Market Overview

Bone graft substitutes are biologics and can be used as an alternative to autologous bone grafts. The substitutes include allograft, demineralized bone matrix, polymers, hydroxyapatite, and several others. These substitutes are used in the treatment of bone defects, union or non-union surgeries, and spinal fusion in orthopedics. Further, multiple benefits of these substitutes, such as their safety, biocompatibility, and osteoconductive to fractured bones, have led to increased adoption of these products over the past ten years. Increased incidences of bone-related diseases, like fractures, degenerative disc disease, and spinal disorders, are driving up the demand for bone grafts and substitutes. The patient population is increasing; consequently, the market is expected to expand further. Development in synthetic substitutes and biological grafts has improved the outcomes in patients, thus leading to its increased adoption in orthopedic surgeries.

Report Coverage

This research report categorizes the market for the US bone graft substitutes market based on various segments and regions forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the United States bone graft substitutes market. Recent market developments and competitive strategies such as expansion, product launch, and development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the U.S. bone graft substitutes market.

Driving Factors

The growing cases of orthopedic disorders have led players in the U.S. bone graft substitutes market to increase their focus on technologies, including antibiotic-eluting products. These products facilitate natural bone healing and minimize the recalcitrance of chronic osteomyelitis from antibiotic-sensitive microorganisms. Within the last few years, the demand for dental bone grafts in dental implantations has increased dramatically because these products provide many benefits. They help to increase the height and thickness of the jawbone, allowing the bone graft substitute to be placed successfully, giving several patients a normal jawline.

Restraining Factors

The drawback associated with the use of substitutes is infection of the soft tissue & bone, severe tissue reactions, and lack of or incomplete bone formation. These disadvantages will unfavorably impact the market for bone graft substitutes in the forecast period.

Market Segmentation

The US bone graft substitutes market share is classified into type and application.

• The synthetic segment is expected to hold a significant market share through the forecast period.

The United States bone graft substitutes market is segmented by type into allograft, demineralized bone matrix (DBM), synthetic, and xenograft. Among these, the synthetic segment is expected to hold a significant market share through the forecast period. This is attributed to the success of this market would majorly depend on factors such as the adoption of synthetic products, growth in bone graft-related surgeries, and the success rate of products.

• The spinal fusion segment is expected to dominate the US market during the projected period.

Based on the application, the United States bone graft substitutes market is divided into spinal fusion, joint reconstruction, foot & ankle, and others. Among these, the spinal fusion segment is expected to dominate the US bone graft substitutes market during the projected period. This is attributed to an increase in the number of surgeries related to lumbar fusion in hospitals. Also, new products being introduced by the market players for spinal injuries would lift the demand for these implants in the country in the years to come.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the United States bone graft substitutes market along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Medtronic
• DePuy Synthes Companies (Johnson & Johnson Services, Inc.)
• Stryker
• Zimmer Biomet
• Smith & Nephew plc
• SeaSpine
• AlloSource
• Bioventus
• MTF Biologics
• Orthofix Holdings, Inc.
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments

• In September 2023, Zimmer Biomet tied up with California-based healthcare technology company HippoFi for a new synthetic biomaterial for bone growth.

Market Segment

This study forecasts revenue at U.S., regional, and country levels from 2020 to 2033. Spherical Insights has segmented the United States bone graft substitutes market based on the below-mentioned segments:

United States Bone Graft Substitutes Market, By Type

• Allograft
• Demineralized Bone Matrix (DBM)
• Synthetic
• Xenograft

United States Bone Graft Substitutes Market, By Application

• Spinal Fusion
• Joint Reconstruction
• Foot & Ankle
• Others